I-Form/Biodesign Europe/Centre for Medical Engineering Research (MEDeng) is currently offering a 3 year postdoctoral researcher position that aims to develop an osteoinduction-augmented magnesium medical Implant for skeletal repair. Magnesium (Mg) and its alloys are emerging as promising implant materials due to their high strength-to-weight ratio and biodegradability. However, the rapid degradation of Mg alloys in physiological conditions poses challenges, potentially leading to early implant failure. This project aims to develop and evaluate CaP-coated porous 3D printed Mg-based implants for orthopaedic and dental applications.
Dublin City University (DCU) is a leading innovative European University, proud to be one of the world’s leading Young Universities. DCU is known as Ireland’s University of Impact, with a mission to ‘transform lives and societies’ and focuses on addressing global challenges in collaboration with key national and international partners and stakeholders.
The I-Form Centre was established by Science Foundation Ireland in late 2017, with a mission to shape the future of manufacturing through high-impact research into the application of digital technologies to materials processing. The Centre is applying developments in digital technologies to materials processing to improve understanding, modelling and control of the manufacturing process, thus increasing the competitiveness of the Irish industry. I-Form brings together expertise in materials science, engineering, data analytics and cognitive computing. One of our key materials processing demonstrators is in the area of Additive Manufacturing or 3D printing, which has the potential to disrupt traditional manufacturing and create new and individualised in areas such as medical devices, aerospace and pharmaceuticals. I-Form operates in close collaboration with a network of companies, as well as leading manufacturing research centres from around the globe and throughout its first phase has recruited a multidisciplinary team of over 120 PhD and Post-Doctoral researchers. The Centre is hosted at University College Dublin with partners and researchers based in Dublin City University, Trinity College Dublin, Maynooth University, University of Galway, Atlantic Technological University, South-East Technological University, University of Limerick and NIBRT.
Biodesign Europe is an established transatlantic scientific research institute that leverages the research infrastructure capacity and expertise at the ASU Biodesign Institute (https://biodesign.asu.edu/) and DCU’s research centres. The focus of Biodesign Europe is to harness the natural design rules of life on this planet and translate nature-inspired solutions to complex grand challenges in health, sustainability and security for global positive impact and driving a sustainable international economy.
MEDeng is a key research centre at Dublin City University focused on translating engineering and materials research into healthcare solutions. The centre has six overarching research themes based at the interface of materials science, engineering and biology - providing the underpinning fundamental research to facilitate the stratified clinical and industrial framework for the development of medical devices and implants for tissue repair and regeneration. Projects are often conducted in close collaboration with leading Irish and international companies and research organisations.
This postdoctoral position offers an exciting job opportunity where the successful candidate will have access to competent technical, infrastructural and administrative support and the opportunity to evolve a multi-faceted skill set. The successful candidate will join an international team of PhD students and postdoctoral researchers and will work in close collaboration with academic, clinical and industry collaborators including PBC Biomed. The postdoctoral researcher will be based in Biodesign Europe and MEDeng at Dublin City University and will work under the supervision of Professor Nicholas Dunne and Dr Tanya Levingstone.
Minimum Criteria
Applicants should have a PhD in Biomedical Engineering, Materials Science, Pharmacy, Biological Science or a cognitive discipline.In addition, it is desirable that the candidate has a strong research track record, experience in development, characterisation, experimental testing, in vitro assessment and in vivo assessment and has a strong knowledge of orthopaedic implants.
In addition, the ideal candidate will have:
- Excellent analytical and problem-solving skills.
- Excellent communication skills, presentation skills and academic article writing skills, as well as a knowledge of the relevant academic literature.
- A high level of interpersonal and teamwork skills.
- Report writing skills.
- Time management skills and an ability to work to deadlines.
- Experience in industry-led research and independent research/project management would be advantageous.
Candidates will be assessed on the following competencies:
Discipline knowledge and Research skills – Demonstrates knowledge of a research discipline and the ability to conduct a specific programme of research within that discipline
Understanding the Research Environment – Demonstrates an awareness of the research environment (for example funding bodies) and the ability to contribute to grant applications
Communicating Research – Demonstrates the ability to communicate their research with their peers and the wider research community (for example presenting at conferences and publishing research in relevant journals) and the potential to teach and tutor students
Managing & Leadership skills - Demonstrates the potential to manage a research project including the supervision of undergraduate students
Essential Training
The postholder will be required to undertake the following essential compliance training: Orientation, Health & Safety, Data Protection (GDPR) and all Cyber Security Awareness Training. Other training may need to be undertaken when required.
Salary Scale: IUA Postdoctoral Researcher Salary Scale – (Point 1) €45,847
Appointment will be commensurate with qualifications and experience and in line with current Government pay policy.
Closing date: Friday, 4th April 2025
For more information on the I-Form Centre, please visit: https://www.i-form.ie/
Informal Enquiries in relation to this role should be directed to:
Professor Nicholas Dunne, Faculty of Engineering and Computing, Dublin City University.
Phone: + 353 (0)1 7005712
Email: nicholas.dunne@dcu.ie
Please do not send applications to this email address, instead apply as described below.
Application Procedure:
Please submit your application through the online system. In order to be considered for the role to which you are applying for, you must upload:
1) Curriculum Vitae
2) Cover Letter
3) Completed application form (blank forms can be downloaded from the bottom of the Vacancy).
I-Form/Biodesign Europe/Centre for Medical Engineering Research (MEDeng) is currently offering a 3 year postdoctoral researcher position that aims to develop a vascularisation-promoting scaffold for bone tissue engineering applications. Bone fractures are a prevalent medical issue impacting millions of people globally each year, necessitating effective and efficient treatment options. While most fractures heal effectively without surgical intervention, non-union fractures and complex bone tissue defects resulting from disease or injury require the use of bone grafts and bone graft substitutes. A critical factor in achieving successful fracture repair is the promotion of new vessel formation within the scaffold; failure to achieve a new blood supply can lead to avascular necrosis, resulting in bone tissue death. This proposal aims to develop a bone scaffold that promotes vascularisation at the site of a bone injury, achieving new bone formation while preventing avascular necrosis.
Dublin City University (DCU) is a leading innovative European University, proud to be one of the world’s leading Young Universities. DCU is known as Ireland’s University of Impact, with a mission to ‘transform lives and societies’ and focuses on addressing global challenges in collaboration with key national and international partners and stakeholders.
The I-Form Centre was established by Science Foundation Ireland in late 2017, with a mission to shape the future of manufacturing through high-impact research into the application of digital technologies to materials processing. The Centre is applying developments in digital technologies to materials processing to improve understanding, modelling and control of the manufacturing process, thus increasing the competitiveness of the Irish industry. I-Form brings together expertise in materials science, engineering, data analytics and cognitive computing. One of our key materials processing demonstrators is in the area of Additive Manufacturing or 3D printing, which has the potential to disrupt traditional manufacturing and create new and individualised in areas such as medical devices, aerospace and pharmaceuticals. I-Form operates in close collaboration with a network of companies, as well as leading manufacturing research centres from around the globe and throughout its first phase has recruited a multidisciplinary team of over 120 PhD and Post-Doctoral researchers. The Centre is hosted at University College Dublin with partners and researchers based in Dublin City University, Trinity College Dublin, Maynooth University, University of Galway, Atlantic Technological University, South-East Technological University, University of Limerick and NIBRT.
Biodesign Europe is an established transatlantic scientific research institute that leverages the research infrastructure capacity and expertise at the ASU Biodesign Institute (https://biodesign.asu.edu/) and DCU’s research centres. The focus of Biodesign Europe is to harness the natural design rules of life on this planet and translate nature-inspired solutions to complex grand challenges in health, sustainability and security for global positive impact and driving a sustainable international economy.
MEDeng is a key research centre at Dublin City University focused on translating engineering and materials research into healthcare solutions. The centre has six overarching research themes based at the interface of materials science, engineering and biology - providing the underpinning fundamental research to facilitate the stratified clinical and industrial framework for the development of medical devices and implants for tissue repair and regeneration. Projects are often conducted in close collaboration with leading Irish and international companies and research organisations.
This postdoctoral position offers an exciting job opportunity where the successful candidate will have access to competent technical, infrastructural and administrative support and the opportunity to evolve a multi-faceted skill set. The successful candidate will join an international team of PhD students and postdoctoral researchers and will work in close collaboration with academic, clinical and industry collaborators including PBC Biomed. The postdoctoral researcher will be based in Biodesign Europe and MEDeng at Dublin City University and will work under the supervision of Professor Nicholas Dunne and Dr Tanya Levingstone.
Minimum Criteria
Applicants should have a PhD in Biomedical Engineering, Materials Science, Pharmacy, Biological Science or a cognitive discipline.In addition, it is desirable that the candidate has a strong research track record, experience in development, characterisation, experimental testing, in vitro assessment and in vivo assessment and has a strong knowledge of orthopaedic implants.
In addition, the ideal candidate will have:
- Excellent analytical and problem-solving skills.
- Excellent communication skills, presentation skills and academic article writing skills, as well as a knowledge of the relevant academic literature.
- A high level of interpersonal and teamwork skills.
- Report writing skills.
- Time management skills and an ability to work to deadlines.
- Experience in industry-led research and independent research/project management would be advantageous.
Candidates will be assessed on the following competencies:
Discipline knowledge and Research skills – Demonstrates knowledge of a research discipline and the ability to conduct a specific programme of research within that discipline
Understanding the Research Environment – Demonstrates an awareness of the research environment (for example funding bodies) and the ability to contribute to grant applications
Communicating Research – Demonstrates the ability to communicate their research with their peers and the wider research community (for example presenting at conferences and publishing research in relevant journals) and the potential to teach and tutor students
Managing & Leadership skills - Demonstrates the potential to manage a research project including the supervision of undergraduate students
Essential Training
The postholder will be required to undertake the following essential compliance training: Orientation, Health & Safety, Data Protection (GDPR) and all Cyber Security Awareness Training. Other training may need to be undertaken when required.
Salary Scale: IUA Postdoctoral Researcher Salary Scale – (Point 1) €45,847
Appointment will be commensurate with qualifications and experience and in line with current Government pay policy.
Closing date: Friday, 4th April 2025
For more information on the I-Form Centre, please visit: https://www.i-form.ie/
Informal Enquiries in relation to this role should be directed to:
Dr Tanya Levingstone, School of Mechanical and Manufacturing Engineering, Faculty of Engineering and Computing, Dublin City University.
Phone: + 353 (0)1 7007718
Email: tanya.levingstone@dcu.ie
Please do not send applications to this email address, instead apply as described below.
Application Procedure:
Please submit your application through the online system. In order to be considered for the role to which you are applying for, you must upload:
1) Curriculum Vitae
2) Cover Letter
3) Completed application form (blank forms can be downloaded from the bottom of the Vacancy).
Cotutelle: Catholic University of Valencia (UCV), Spain. Biomaterials and Bioengineering Laboratory
MORE INFORMATION, GUIDE FOR APPLICANTS AND APPLICATION FORM: HERE
The new recruit will join the Littoral, Environment and Society laboratory (LIENSs)
Scientific Objectives
The main objective of this PhD thesis is to develop, characterize, and evaluate antiviral materials for biomedical applications using bioactive metabolites extracted from marine bacteria from La Rochelle Collection. The specific objectives are as follows:
Isolation and identification of antiviral metabolites by extracting and characterizing bioactive compounds with antiviral activity from marine bacterial cultures.
Formulation of antiviral materials by developing composite materials by incorporating the identified metabolites into alginate and chitosan matrices, ensuring uniform distribution and stability of the bioactive agents.
Evaluation of antiviral efficacy by assessing the antiviral activity of the developed materials against a range of viral pathogens, with emphasis on clinically relevant strains.
Characterization of material properties by evaluating the physicochemical, mechanical, and biocompatibility properties of the developed antiviral materials to ensure they meet biomedical standards.
Mechanistic studies by investigating the mechanisms underlying the antiviral activity of the developed materials to elucidate their modes of action.
Scientific Challenges
The project entails several scientific challenges:
Extraction and stability of marine-derived metabolites by ensuring efficient extraction, purification, and stability of bioactive metabolites from marine bacteria, while maintaining their antiviral efficacy during processing and integration with polymers.
Material formulation and uniformity by achieving homogeneous integration of antiviral agents within alginate and chitosan matrices to ensure consistent antiviral effects while preserving mechanical and biocompatibility properties.
Viral testing and safety assessment by conducting rigorous antiviral assays, while ensuring the developed materials are non-toxic and safe for biomedical applications.
Optimization of material properties by balancing antiviral efficacy with essential properties such as biodegradability, mechanical strength, biocompatibility, and processability to meet the diverse needs of biomedical applications.
Expected Results
Development of antiviral material by integrating marine-derived bioactive metabolites into alginate and chitosan matrices.
Broad-spectrum antiviral activity against a range of viral pathogens, with the potential for use in a variety of biomedical applications.
Production of biocompatible and functional materials with desirable mechanical, physicochemical, and biocompatibility properties suitable for biomedical applications.
Insights into the molecular mechanisms of antiviral action, paving the way for the rational design of future antiviral materials.
This project represents a pioneering effort to combine marine-derived bioactive compounds with biocompatible polymers, aiming to produce antiviral materials with broad applications in biomedicine. It holds promise to address unmet needs in combating viral infections through innovative and sustainable solutions.
Where to apply
E-mail: eudocs_cofund@univ-lr.fr
Requirements
Research Field: Biological sciences
Education Level: Master Degree or equivalent
Benefits
36-month PhD contract based in La Rochelle (17).
Salary: €2700 gross per month. You are registered with the Doctoral School for the duration of your contract and benefit from the DS's training offer, in particular cross-disciplinary activities such as MT180, the doctoral students' colloquium, etc.
Recruitment open to anyone with a RQTH (Qualified Health and Disability certificate).
Eligibility criteria
All applications will first go through an eligibility check based on:
Compliance with the Marie Sklodowska-Curie mobility rule: applicants must not have resided or carried out their main activity (work, studies, etc.) in France for more than 12 months in the last three years before the call deadline. Compulsory national service, short stays such as holidays and time spent as part of a procedure for obtaining refugees status under the Geneva Convention (1951 Refugee Convention and the 1967 Protocol) are not taken into account.
Ability to prove a master level. Applicants already in possession of a PhD title are not eligible. Researchers who have successfully defended their doctoral thesis, but who have not yet formally been awarded the doctoral degree will not be eligible.
Selection process
How to apply?
The application should be completed in English and submitted along with the mandatory supporting documents.
You must provide a file named as follows “ProjectAcronym_NameApplicant” with:
Your resume (giving a detailed account on your marks, and assessment of your level of English) – max 5 pages.
A cover letter explaining your motivation – max 2 pages.
A proof of identity (passport or ID card)
Master’s degree transcript (or equivalent)
Filled application form (fully dated and signed)
Applications must be sent no later than 15th March 2025 at eudocs_cofund@univ-lr.fr
For any question, please refer to the FAQ or contact the following email address eudocs_cofund@univ-lr.fr
INCOMPLETE APPLICATIONS WILL NOT BE CONSIDERED.
Provisional timetable
13 January – 15 March 2025: Call for applicants
March – May 2025: Peer review by ESF
30 June - 3 July 2025: Interviews by the Interview committee
July 2025: Final decision
From September 2025: Beginning of the thesis
Cotutelle: Catholic University of Valencia (UCV), Spain. Biomaterials and Bioengineering Laboratory
MORE INFORMATION, GUIDE FOR APPLICANTS AND APPLICATION FORM: HERE
Scientific Objectives
The main objective of this PhD thesis proposal is to develop antimicrobial materials through the integration of DL to predict and optimize the antimicrobial efficacy of new compounds and material composites against viruses, bacteria and fungi. Key objectives include:
Designing novel antimicrobial materials by applying AI-based models (specifically DL) to identify the most promising molecular structures for antimicrobial activity.
Optimization of material properties, including biocompatibility, stability, and antimicrobial efficacy, using data-driven approaches powered by AI.
Testing and validation of the developed materials to assess their effectiveness against viruses, bacteria and fungi in in vitro experimentation under biosafety level 2 conditions.
Testing that the developed antimicrobial materials are safe for human beings testing their toxicological aspects in in vitro experimentation under biosafety level 2 conditions.
Identification of key factors influencing antimicrobial activity to guide the rational design of future materials.
Scientific Challenges
This research faces several significant scientific challenges:
For Dl to effectively predict antimicrobial properties, high-quality, diverse datasets of molecular interactions and material properties are required. Gathering and curating these datasets can be challenging.
The rational design of antimicrobial materials requires understanding the complex interactions between material properties, pathogens, and the environment. These interactions are difficult to predict without sophisticated AI tools.
While the focus is on antimicrobial efficacy, it is also crucial that the materials are biocompatible and stable for biomedical applications. Balancing these factors while maintaining high antimicrobial activity presents a challenge.
To integrate AI and experimental validation to translating AI predictions into real-world applications requires extensive experimental validation to confirm the accuracy of the DL predictions.
Expected Results
This research is expected to yield several significant outcomes:
The creation of novel antimicrobial materials with enhanced antibacterial, antifungal and/or antiviral properties that can be applied in various biomedical fields, such as wound healing, medical devices, and drug delivery systems.
The development of a predictive AI framework using Dl that can guide the design of antimicrobial materials, reducing the need for trial-and-error experiments and speeding up the material development process.
A deeper understanding of the structure-activity relationships that govern the antimicrobial properties of materials, providing insights into how to optimize materials for specific pathogens.
A validated approach for integrating AI-driven predictions with experimental testing, enabling more efficient development of future antimicrobial materials.
The successful completion of this project will contribute to addressing the global health challenge of antimicrobial resistance and provide a scalable approach for designing innovative materials with specific biomedical applications. By leveraging AI, this research will pave the way for the development of advanced materials that could significantly impact healthcare and the pharmaceutical industry.
Where to apply
E-mail: eudocs_cofund@univ-lr.fr
Requirements
Research Field: Computer science
Education Level: Master Degree or equivalent
Benefits
36-month PhD contract based in La Rochelle (17).
Salary: €2700 gross per month. You are registered with the Doctoral School for the duration of your contract and benefit from the DS's training offer, in particular cross-disciplinary activities such as MT180, the doctoral students' colloquium, etc.
Recruitment open to anyone with a RQTH (Qualified Health and Disability certificate).
Eligibility criteria
All applications will first go through an eligibility check based on:
Compliance with the Marie Sklodowska-Curie mobility rule: applicants must not have resided or carried out their main activity (work, studies, etc.) in France for more than 12 months in the last three years before the call deadline. Compulsory national service, short stays such as holidays and time spent as part of a procedure for obtaining refugees status under the Geneva Convention (1951 Refugee Convention and the 1967 Protocol) are not taken into account.
Ability to prove a master level. Applicants already in possession of a PhD title are not eligible. Researchers who have successfully defended their doctoral thesis, but who have not yet formally been awarded the doctoral degree will not be eligible.
Selection process
How to apply?
The application should be completed in English and submitted along with the mandatory supporting documents.
You must provide a file named as follows “ProjectAcronym_NameApplicant” with:
Your resume (giving a detailed account on your marks, and assessment of your level of English) – max 5 pages.
A cover letter explaining your motivation – max 2 pages.
A proof of identity (passport or ID card)
Master’s degree transcript (or equivalent)
Filled application form (fully dated and signed)
Applications must be sent no later than 15th March 2025 at eudocs_cofund@univ-lr.fr
For any question, please refer to the FAQ or contact the following email address eudocs_cofund@univ-lr.fr
INCOMPLETE APPLICATIONS WILL NOT BE CONSIDERED.
Provisional timetable
13 January – 15 March 2025: Call for applicants
March – May 2025: Peer review by ESF
30 June - 3 July 2025: Interviews by the Interview committee
July 2025: Final decision
From September 2025: Beginning of the thesis
The dark side of muscular dystrophies: targeting endothelialmesenchymal transition in the dystrophic microenvironment through a biofabricated human muscle-on-a-chip
The Regenerative Medicine Technologies (RMT) Lab is part of the Laboratories for Translational
Research of Ente Ospedaliero Cantonale located in Bellinzona (Switzerland).
Strategic research areas of the RMT Lab are: in vitro disease modeling through biofabrication (e.g. age-
related diseases, cancer metastases, musculo-skeletal diseases); design of novel technologies for drug
screening; personalized medicine applications using human tissue biopsies. To promote the
advancement of these research areas, the RMT Lab combines microfluidics and microphysiological
systems, 3D (bio)printing and computational simulations.
The RMT Lab invites applications for a fully funded Ph.D. position in Biomedical Sciences for conducting
research in the project entitled “The dark side of muscular dystrophies: targeting endothelial-
mesenchymal transition in the dystrophic microenvironment through a biofabricated human
muscle-on-a-chip”.
The project
The lab has recently granted funding from the Fondation Suisse de Recherche sur les Maladies
Musculaires. The 3 years project will deal with the identification of biological mechanisms driving blood
vessel degeneration in skeletal muscle dystrophies.
The project involves the biofabrication of a human muscle-on-a-chip embedding contractile muscle
bundles and perfusable microvascular networks. Starting from patient-derived cells, the project aims at
dissecting the heterotypic cell-cell interactions occurring within the dystrophic muscle microenvironment
through a combination of high-content imaging and next-gen sequencing techniques. The lab has
access to cutting-edge facilities (e.g. bulk and single-cell RNAseq; spatial transcriptomics; mass
spectrometry; confocal, multi-photon and electron microscopy) which are shared with the Institute for
Research in Biomedicine and the Institute of Oncology Research within a dynamic, multidisciplinary
and collaborative environment.
The Ph.D. Position
The doctoral student will be enrolled in the PhD track in Biomedical Sciences (PhD Biomedical
Sciences). The doctoral student will work under the scientific supervision of Prof. Simone Bersini
(https://search.usi.ch/en/people/af37e00b27d5199e68bb294f19e50006/bersini-simone).
The successful candidate will be offered the possibility to work in a dynamic research team and in a
multidisciplinary and international scientific environment.
The PhD candidate will collaborate in the development of the institute research agenda. He or she will
have the task of setting up a collection of data for his or her dissertation, while at the same time
participating in a variety of tasks related to the research streams in which he/she is involved.
The PhD candidate is also asked to present papers at scientific conferences and produce publications
for scientific journals.
Candidates’ profile
Ideal candidates should satisfy the following requirements:
• A Master (or equivalent title) in any Life Sciences or related disciplines including Bioengineering. Priority
given to Muscle Biology or Vascular Biology background
• High personal interest in organ-on-a-chip, 3D (bio)printing, microfabrication
• Experience with (or strong commitment to learn): cell culture (preferred if 3D cultures with hydrogels
and muscle cells or endothelial cells), imaging (confocal microscopy, preferably with 3D cultures and
using high-content screening systems), standard biological techniques (qPCR, western blot, elisa,
immunofluorescence), design and microfabrication of microphysiological systems
• Good skills in oral and written English (official language of the Ph.D. program)
• Self-motivation and exceptional commitment to experimental goals and deadlines
• Strong organizational skills and ability to work independently as well as in a team
• Critical data analysis and troubleshooting
• Effectively communicate experimental data, maintain records and write manuscripts
• Motivation to engage in the elaboration of a PhD dissertation. Interest for teaching and tutoring students
and availability to collaborate with colleagues (engage in scientific dialogue, listen and think critically)
are required.
Contract terms
Admission to the Ph.D. program is highly competitive. Admission decisions are based on the
candidate’s background, interests, attitude and potential for academic achievement. Successful
enrolment in the Ph.D. program and the position as doctoral researcher are not compatible with a further
professional activity.
The successful candidate will work as research assistant at the RMT Lab, and will have the possibility
to interact with an international network of collaborators.
Workplace is RMT Lab, located in Bellinzona, Switzerland. Availability to travel to other parts of
Switzerland and abroad (for purposes of collaboration and research) is required.
Starting date is June 1, 2025 (possibility to anticipate or postpone upon request). The position will be
kept open until a suitable candidate has been found.
The Application
Applications should contain: (1) a letter in which the applicants describe their research interests and the
motivation to apply, (2) a complete CV, (3) copies of relevant diplomas, certificates as well as the full
transcript of records that prove the candidates’ eligibility for doctoral studies, (4) an electronic version
of a research work (Master thesis or other scientific publication). The latter must be accompanied by a
short summary in English (1 page maximum). (5) Two references (support letters are not necessary at
this stage of evaluation).
Please send your application in electronic form or requests for further information to
simone.bersini@eoc.ch (please use the following subject: PhD-Muscle)
The RMT Lab invites applications for a fully funded Ph.D. position in Biomedical Sciences for conducting research in the project entitled “A high-throughput microphysiological platform to analyze the role of the aging human vasculature in melanoma metastases”.
The 4 years project will deal with the identification of biological mechanisms driving the formation and progression of metastases in presence of aging blood vessels with the final goal of identifying translational opportunities to block this process.
The project involves the biofabrication of 3D microvascular networks (main focus on the blood brain barrier), their integration with high-throughput culture systems and the analysis of blood vessel-cancer cell interaction through multiple next-gen sequencing techniques and high-content screening.
The Polymers, Biopolymers Surfaces (PBS) Laboratory (UMR CNRS 6270) is seeking a postdoc with a strong background in immunoengineering, biomaterials and/or polymer chemistry.
The successful candidate will contribute developing advanced biomaterials for cancer immunotherapy. This project aims to harness the potential of biomaterials to improve the delivery and efficacy of T cells in solid tumors, significantly impacting human health and expediting clinical translation.
The postdoctoral researcher will be employed by CNRS, Europe's largest fundamental science agency, and conduct research under Dr. Sidi A. Bencherif at the Polymers, Biopolymers Surfaces (PBS) Laboratory (UMR CNRS 6270), located at University Rouen Normandy. PBS, a joint research unit of CNRS and the National Institute of Applied Sciences (INSA) Rouen Normandy, is associated with the Doctoral School of Chemistry and an interregional research center. PBS aims to develop innovative high-performance polymers through macromolecular chemistry, employing physical, physico-chemical, and biological approaches, and evaluating their functions in diverse environments, including biological systems. The PBS Laboratory comprises 46 permanent staff members, including 11 professors, 17 assistant professors, 2 CNRS researchers, 7 ITAs, and 9 BIATSSs. Researchers at PBS possess diverse expertise spanning chemistry, biology, and materials science, focusing on areas such as antimicrobial biomaterials, brain tissue reconstruction, and 3D bioprinted constructs for skin tissue engineering. Collaboration with Rouen University Hospital and international partners (e.g., USA, Europe) will further advance our research and facilitate translating research into clinical trials.
Find more information and apply here.
The AO Research Institute (ARI) Davos is seeking a postdoc with a strong background in biopolymer chemistry and biomaterials!
The successful candidate will contribute developing dynamic materials for tissue engineering/regenerative medicine and drug/cell delivery for the musculoskeletal system. The position will be involved in ongoing research concerning the chemical modification of biopolymers, their biofabrication to achieve constructs with dynamic characteristics to foster cell invasion and thereby tissue regeneration. Part of the work is a collaboration with the Baltic Biomaterials Center of Excellence in Riga, Latvia (https://bbcentre.eu/), and the successful candidate will be also involved in educational activities to share best practices between ARI and BBCE.
A Post-doc position is available within the ERC Starting “OviChip” Project, which is comprised of a team of researchers with the aim to develop a 3D in vitro model of a human Fallopian Tube (an “on chip” model) to study human (in)fertility. The fallopian tube connects the ovary to the uterus, helping to guide an egg to the uterus, directing sperm to meet the egg on its journey, and facilitating both fertilization and early embryo development. The Post-doc will use a 3D in vitro model of the oviduct, with a focus on studying how the oviduct microenvironment can be influenced by systemic (e.g. hormone, immune state) and environmental factors (e.g. toxins) and, ultimately, how that impacts early embryo development. The position will be for 1 year initially, which can be extended for an additional 2 years (3 years total) pending an annual evaluation.
Responsibilities
Activities for this project include organoid cell culture, embryo isolation (mouse), and cell characterization. There will also be some expectations of fabricating 3D in vitro environments and fluidic culture devices. A particular focus will be on validating system readout, including chromosomal abnormalities, gene/transcriptome analysis as well as direct visualization within the in vitro system of embryo response (e.g. stress, cleavage rate) via novel (multiphoton) microscopy methodologies to visualize in real-time dynamic cell behaviour within 3D cell culture platforms.
Qualifications
Applicants for the Post-doc position in the field of embryo development and 3D in vitro oviduct models should have a M.Sc. degree in biology, and a Ph.D. that has some overlap with the post-doc description. A strong plus will be past experience working with animal models for reproduction studies and it is advisable to have expertise in relevant biological readouts and/or some experience using (complex) in vitro mammalian cell culture. In the supporting role for ongoing PhD projects, experience/knowledge relating to the immune system or sperm cells is also considered a strong addition. Excellent and proven knowledge of scientific English, both in speaking, reading, and writing is required.
More information and applications submission can be found via the link below:
A PhD position is available within the ERC Starting “OviChip” Project, which is comprised of a team of researchers with the aim to develop a 3D in vitro model of a human Fallopian Tube (an “on chip” model) to study human (in)fertility. The fallopian tube connects the ovary to the uterus, helping to guide an egg to the uterus, directing sperm to meet the egg on its journey, and facilitating both fertilization and early embryo development. The PhD student will further develop and use a 3D in vitro model of the oviduct, with a focus on studying how sperm cells behave to identify novel aspects of reproduction and underlying causes of infertility.
Responsibilities
Activities for this project include organoid cell culture, sperm cell isolation, and cell characterization. At the same time, there will also be the fabrication of 3D in vitro environments and fluidic culture devices, with the goal of increasing model fidelity in terms of structure and having different cell types be present. A particular focus will be on validating system readout, through the implementation of fluid flow regimes within the in vitro system coupled with novel (multiphoton) microscopy methodologies to visualize in real-time dynamic cell behaviour within 3D cell culture platforms.
Qualifications
Candidates should have an M.Sc. degree in either biofabrication, regenerative medicine, biomedical sciences, or applied biology, with already proven experience in cell culture, in particular in 3D culture systems (e.g. hydrogels, microfluidics). Past experience that combines cell culture with fluid flow and characterization cell response to fluid shear will be a strong addition. Excellent and proven knowledge of scientific English, both in speaking, reading, and writing is required.
More information and applications submission can be found via the link below:
Applications are invited from suitable candidates for 25 full-time fixed term Marie Skłodowska-Curie Doctoral Fellows (DFs) with CÚRAM, SFI Research Centre for Medical Devices at University of Galway. These positions are available from November 2024 for a period of 48 months. MedDevDoc is an advanced Industry-Academia Training, Career Development, and Mobility Fellowship Programme.
You can learn more about our vision, research platforms, a consortium of academic and industry partners, Science policy and advocacy, and public engagement on our website CÚRAM - CÚRAM (curamdevices.ie)
CÚRAM MedDevDoc Fellowships are open to applicants of any nationality, resident anywhere in the world (see eligibility criteria in a guide for applicants), seeking a prestigious career development fellowship in medical device research and development based at one of the following host organisations: University of Galway (GALWAY), University College Dublin (UCD),The Royal College of Surgeons in Ireland (RCSI), TrinityCollege Dublin (TCD), University of Limerick (UL), Dublin City University (DCU), Technological University of the Shannon (TUS), University CollegeCork (UCC), National Institute forBioprocessing Research and Training (NIBRT) and Technological University Dublin (TU Dublin).
MedTrain+ Marie Skłodowksa Curie Fellowship Programme 2023
CÚRAM: Biomedical Sciences Building, University of Galway
Ref. No. University of Galway 305-23
Applications are invited from suitably qualified candidates for 50 Marie Skłodowska-Curie Postdoctoral Fellows (PFs) (two levels of experienced researchers) (25 positions available in Call 2) at CÚRAM, SFI Research Centre for Medical Devices. MedTrain+ is an advanced Industry-Academia Training, Career Development, and Mobility Fellowship Programme. Positions are available for 36 months full-time from August 2024 onwards.
The projects will encompass the broad area of Medical Device Research and Development, including Biomaterials and Drug Delivery Devices, MedTech AI, Machine Learning, Medical Imaging and Soft Robotics, Immuno Engineering and Education and Public Engagement (EPE) and Science Advocacy Programmes and Regulatory. The research proposals shall be focused on Neuroscience as an area for research except for Education and Public Engagement (EPE) and Science Advocacy Programmes and Regulatory.
For More details about MedTrain+:
https://curamdevices.ie/curam/research/eu-projects/medtrain/apply/
For info and application procedure please visit the project website https://rebone.eu/
More details here : https://www.kuleuven.be/personeel/jobsite/jobs/60289370?hl=nl&lang=nl
Synthesis of photo-crosslinkable polymers for the development of a cornea-on-a-chip
More details
https://jobs.tuwien.ac.at/Job/
The CCCF hosts a state-of-the-art cell culture lab for mammalian cells. Equipment includes laminar flow hoods, incubators, centrifuges, refrigerators/freezers, microscopes, automated cell counters, a FACS/cell sorter, a bioprinter, a histology lab and molecular biology equipment. With this, the CCCF provides space, equipment, supplies and training for TU Wien research labs from disciplines as diverse as mechanics, physics, chemistry and electronics.
Tasks:
- Provide scientific, technical, and administrative leadership and expertise in the operations of the Cell Culture Core Facility
- Develop and maintain operational policies and procedures
- Manage facility use
- Provide training and technical support for facility users
- Perform research in collaboration with facility users
- Teaching and training of students
- Upkeep of supplies and equipment
- Promote the facility internally and externally
- Maintain strategic overview and exchange information with other facilities
- Assure compliance with safety regulations and university policies
- Develop facility strategic plan
- Hire, train, and manage personnel
- Develop and provide custom made analysis tools for research groups to address specific research questions
Your profile:
- Studies and PhD in cell biology, molecular biology or closely related field
- Experience in mammalian cell culture, primary cell culture, 3D cell culture models
- Experience in genetic modification of mammalian cells (CRISPR/Cas9, plasmid vectors)
- Experience in molecular biology techniques (e.g. plasmid generation, PCR, ELISA, Southern Blotting)
- Experience in imaging techniques (e.g. fluorescence microscopy, immuno-labeling, life cell imaging and alternative imaging techniques) and histology
- Experience in flow cytometry
- Ability to provide custom made analysis tools for research groups to address specific research questions
- Good understanding of mathematical models, computational statistical approaches and bioinformatics, preferably including machine learning
- Demonstrated experience in planning and conducting scientific research as exemplified by high quality peer-reviewed publications
- Ability to communicate with and understand the requirements of scientists from different disciplines
- Experience in teaching and student supervision
- Ability of working in a team
- Ability to supervise and train employees
- Ability to organize own time and prioritize
- Excellent communication skills in English and German
- Management skills in organization of (support) research units
Previous experience as facility or lab manager or similar activities, postdoctoral/research experience, preferentially abroad, experience with international collaborations, interaction with microscopy and/or flow cytometry instrument vendors to develop specific applications will be considered as assets.
We offer:
- An innovative highly interdisciplinary environment
- A management position that allows self-reliant decision making
- New state-of-the-art equipment
- Excellent opportunities for personal development in a scientifically stimulating environment
- Flexible working hours, reconciling career and family, a range of according university services
People with special needs are equally encouraged to apply. In case of any questions, please contact the confidant for disabled persons at the university, Mr. Gerhard Neustätter.
We look forward to receiving your application until September 21st, 2023. Please note: The application deadline has been extended to October 05th, 2023.
Application documents:
- A motivation letter listing significant achievements, relevant experience referring to the description of this position and indicating preferred start date (no longer than 2 pages)
- CV, including education/ internship/ employment /publication record /mentoring activities
- 1-3 reference letters and contact details of people who can provide a reference
A new vacancy is available online for a full-time position as Professor of Chemical Engineering: Modeling Transport Phenomena and Properties for Soft Matter in Bio- and Health Applications:
https://www.kuleuven.be/personeel/jobsite/jobs/60212841?hl=en&lang=en