Expertise
My research combines biomaterials engineering, organoid technology, and microphysiological systems to develop human-relevant in vitro models with precise control over the tissue microenvironment. My expertise lies particularly in the design of synthetic and dynamic hydrogel systems, including PEG-based and supramolecular biomaterials, whose biochemical and mechanical properties can be independently tuned to regulate cell behaviour. I integrate these materials with human intestinal organoids, immune cells, and other tissue-relevant cell types in microfluidic and organ-on-chip platforms. A major focus of my work is the engineering of extracellular-matrix-inspired environments in which parameters such as stiffness, viscoelasticity, ligand presentation, spatial organization, and inflammatory signals can be systematically manipulated. I also have experience in microfabrication, hydrogel photopatterning, organoid culture, multicellular co-culture systems, and molecular and functional characterization of engineered tissues. By combining these approaches, I aim to dissect how defined biochemical, mechanical, and cellular cues regulate tissue function and disease-associated phenotypes in human models, particularly in the context of intestinal inflammation, sex differences, and women’s health.