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Video of Riccardo Levato (Jean Leray award 2021).

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First and Last Name: Niels Willemen
Student/PhD/Postdoc: PhD student
Institute: University of Twente
Department: Leijten Lab
Group leader: Jeroen Leijten
A Colourful Cuddle
In this experiment, human mesenchymal stem cells (stained with phalloidin) and cell-adhesive microgels (stained with ATTO565 (red) and FITC (green)) self-assembled into a living microtissue. The properties of these cell-adhesive microgels are both physically and chemically tuneable. Moreover, the cell-adhesive microgels are able to direct the behaviour of the cells, for example by influencing cell fate by microgel stiffness.
Instrument used to produce the image: Zeiss LSM880


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Małgorzata POPIS

MSc
Małgorzata POPIS; POLAND
Polbionica Ltd

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Biography
Currently working as Biotechnologist at Polbionica Lts, Warsaw, Poland. Adam Mickiewicz University graduate with a Master's Degree in Biotechnology in English, specialized in the area of regenerative medicine. In the course of her development path completed a scientific internship at the Oklahoma Medical Research Foundation. Awarded with the Scientific Scholarship of the Marshal of the Wielkopolska Region and the Rector's Scholarship of the Adam Mickiewicz University. Co-author of scientific publications, including articles related to isolation, cultivation and clinical use of stem cells.

Expertise
Currently involved in project on 3D bioprinted liver tissue with the vascular system as an innovative model for assessing the toxicity of drugs and the effectiveness of anti-cancer therapies. Completed research project "Optimization of the method of isolation and culture together with the characteristics of the properties of human mesenchymal stem cells from Wharton's jelly". Completed a research project "Antibody interactions with the spike protein of SARS-CoV-2 variants of concern". Completed a research project "Mutation analysis in the TOMM20 gene in patients diagnosed with Parkinson's disease".
Publications
1) Popis,M.,Konwerska,A.,Partyka,M.,Wieczorkiewicz,M.,Ciesiółka,S.,Stefańska,K.,Spaczyńska,J.,Golkar-Narenji,A.,Jeseta,M.,Bukowska,D.,Mozdziak,P. & Dyszkiewicz-Konwińska,M.(2021).Mesenchymal stem cells and their secretome - candidates for safe and effective therapy for systemic lupus erythematosus. Medical Journal of Cell Biology,9(3) 110-122. https://doi.org/10.2478/acb-2021-0016 2) Stefańska, K., Ożegowska, K., Hutchings, G., Popis, M., Moncrieff, L., Dompe, C., Janowicz, K., Pieńkowski, W., Gutaj, P., Shibli, J. A., Prado, W. M., Piotrowska-Kempisty, H., Mozdziak, P., Bruska, M., Zabel, M., Kempisty, B., & Nowicki, M. (2020). Human Wharton's Jelly-Cellular Specificity, Stemness Potency, Animal Models, and Current Application in Human Clinical Trials. Journal of clinical medicine, 9(4), 1102. https://doi.org/10.3390/jcm9041102 3) Kranc,W.,Popis,M.,Dompe,C.,Golkar-Narenji,A.,Jeseta,M.,Mozdziak,P.,Kistanova,E.,Makarevich,A.,Machatkova,M.,Bukowska,D.,Prochazka,R.,Jaśkowski,J.,Ratajczak,K.,Sobolewski,J. & Antosik,P.(2021).New gene markers involved in regulation of granulosa cells development