Mariella ROSALIA profile

Mariella graduated in Pharmacy at University of Pavia in 2020 presenting a Master’s thesis on the antibacterial activity of antibiotic functionalized glasses, under the supervision of Prof. Pietro Grisoli. In 2013 and in 2012 she had the opportunity of internships, respectively at the Department of Biotechnology of the University of Insubria in Varese (Italy) and in a Q&C Laboratory at Lanxess GmbH in Krefeld-Uerdingen (Germany). In 2022 she spent 5 months at Trinity College Dublin (Ireland), working in the LBCAM research group headed by Prof. Adriele Prina-Mello. In 2023 she spent 3 months at the Institute for Biomaterials at the Friedrich-Alexander University in Erlangen (Germany) under the supervision of Prof. Aldo Boccaccini. Currently, Mariella is concluding her PhD in Chemical-Pharmaceutical Sciences and Industrial Innovation at University of Pavia, under the supervision of Prof. Bice Conti and Prof. Ida Genta, working on the development of vascular grafts manufactured with bioresorbable materials and suitable for local drug delivery of antibiotics and immunomodulatory molecules.

Mariella's main expertise is on the production of tissue engineering scaffolds using electrospinning and solvent casting/particulate leaching techniques. The preferred biomaterials are bioresorbable polyesters, including PLGA, PCL and PGS. Encapsulation of drugs, including antibacterial and immunomodulatory drugs, is also performed to obtain controlled drug release systems and their efficacy is tested throughout in vitro cell and antibacterial assays.